The REP1 Polyclonal Antibody from MyBioSource.com is a Goat Polyclonal antibody to CHM, CHML, HSD-32, and REP1. This antibody recognizes Human, Mouse, Rat, Bacteria/Archaea, Bovine, Canine, Chicken/Bird, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Non-Human Primate, Porcine, Rabbit, and Sheep antigen. The REP1 Polyclonal Antibody has been validated for the following applications: Western Blot.
Description
Choroideremia (Rab escort protein 1)
REP1 is the component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Mutations in this protein are a cause of a type of retinal degeneration, called choroideremia